Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add filters








Language
Year range
1.
Rev. méd. Chile ; 146(10): 1175-1183, dic. 2018. tab, graf
Article in Spanish | LILACS | ID: biblio-978753

ABSTRACT

Diabetes Mellitus (DM) and obesity are a public health problem in Chile. Bariatric surgery is the most effective treatment alternative to achieve a significant and sustained weight reduction in patients with morbid obesity. The results of controlled clinical trials indicate that, compared to medical treatment, surgery for obese patients with DM2 allows a better control of blood glucose and cardiovascular risk factors, reduces the need for medications and increases the likelihood for remission. Consensus conferences and clinical practice guidelines support bariatric surgery as an option to treat DM2 in Class III Obesity (Body Mass Index (BMI) > 40) regardless of the glycemic control and the complexity of pharmacological treatment and in Class II Obesity (BMI 35-39,9) with inadequate glycemic control despite optimal pharmacological treatment and lifestyle. However, surgical indication for patients with DM2 and BMI between 30-34.9, the most prevalent sub-group, is only suggested. The Chilean Societies of Endocrinology and Diabetes and of Bariatric and Metabolic Surgery decided to generate a consensus regarding the importance of other factors related to DM2 that would allow a better selection of candidates for surgery, particularly when weight does not constitute an indication. Considering the national reality, we also need a statement regarding the selection and characteristics of the surgical procedure as well as the role of the diabetologist in the multidisciplinary team.


Subject(s)
Humans , Diabetes Mellitus, Type 2/surgery , Bariatric Surgery/methods , Obesity/surgery , Societies, Medical , Body Mass Index , Chile , Risk Factors , Treatment Outcome , Medical Illustration
3.
Rev. chil. cir ; 58(4): 293-297, ago. 2006. tab
Article in Spanish | LILACS | ID: lil-475802

ABSTRACT

En el caso de pacientes con cáncer gástrico T4, puede estar indicada la quimiorradioterapia si no es posible la resección de las estructuras infiltradas. Analizamos 10 pacientes con cáncer gástrico irresecable (8 hombres, 2 mujeres) tratados por nosotros en el periodo 2003-2005. Después de la laparotomía exploradora, los pacientes con cáncer gástrico localmente avanzados e irresecables son tratados con RT-QT concomitante 2 semanas después de la laparotomía. El tratamiento consistió en radioterapia a dosis de 45 Gy en 25 fracciones de 1.8 Gy, 5 veces por semana por 5 semanas sobre estómago y linfáticosregionales, y 5 FU en 1ª y 5º semana (425mg/m2) o Capecitabina 825 mg/m2 diarios, en dos dosis, cada12 hrs. Un mes después se realiza la segunda laparotomía con resección del estómago y linfadenectomía en casos de remisión total o parcial de la enfermedad. Todos los carcinomas fueron proximales. Nueve pacientes se reintervinieron, un paciente tuvo progresión de la enfermedad. Un paciente fue nuevamente irresecable y ocho fueron sometidos a una gastrectomía total D2. Se logró respuesta patológica completa en tres casos (no había cáncer residual en el estómago ni en los ganglios) y parcial en cinco. Creemos que en cáncer gástrico T4 localmente irresecable la RT-QT seguida de cirugía es una buena alternativa terapéutica.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Adenocarcinoma , Stomach Neoplasms/drug therapy , Stomach Neoplasms/radiotherapy , Antimetabolites, Antineoplastic/therapeutic use , Chemotherapy, Adjuvant , Combined Modality Therapy , Deoxycytidine/therapeutic use , Fluorouracil/therapeutic use , Neoplasm Invasiveness/prevention & control , Neoplasm Metastasis/prevention & control , Neoplasm Staging , Stomach Neoplasms/surgery , Radiotherapy, Adjuvant , Treatment Outcome
SELECTION OF CITATIONS
SEARCH DETAIL